FAM126B

Across TCGA pan-cancer cohorts, FAM126B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM126B data layer compared with 21 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FAM126B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM126B expression acts as an unfavorable survival marker.

COAD are the cancer types where FAM126B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.111	0.871	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

FAM126B–COAD (OS)

Open the COAD breakdown →