FAM126B

Across TCGA patient cohorts, FAM126B protein abundance is significantly associated with the RNA expression of many other genes, with 6,547 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM126B-associated genes across cancer lineages are SRM, FBXO34, and TRAPPC6B. Each is linked with FAM126B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM126B-to-partner and partner-to-FAM126B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM126B versus SRM in CCRCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM126B→partner) and Y-score (partner→FAM126B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SRM →	-0.553	-0.291	<.001	<.001	3	3
UCEC	FBXO34 →	+0.429	+0.292	.004	<.001	3	3
OV	TRAPPC6B →	+0.377	+0.323	.002	.001	3	3
UCEC	SGMS1 →	+0.598	+0.304	<.001	<.001	3	3
OV	GPC2 →	-0.784	-0.354	.002	.008	3	3
UCEC	STYK1 →	+0.779	+0.164	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,547 associations by consensus.

FAM126B vs SRM — CCRCC

Explore this scatter interactively →