FAM126B

Across TCGA cell cohorts, FAM126B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM126B-associated genes across cancer lineages are LRRC3B, OR1K1, and PRODH2. Each is linked with FAM126B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM126B-to-partner and partner-to-FAM126B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC3B grouped by FAM126B-low versus FAM126B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM126B→partner) and Y-score (partner→FAM126B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LRRC3B →	+0.022	+3.930	<.001	.003	3	2
SKIN	OR1K1 →	+0.141	+4.347	.001	.001	3	1
SKIN	PRODH2 →	+0.039	+4.510	<.001	.001	3	1
LARGE_INTESTINE	CNTN3 →	+0.596	+4.199	<.001	.007	3	1
LARGE_INTESTINE	MYOD1 →	+0.014	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ZFP92 →	+0.557	+4.289	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

LRRC3B by FAM126B expression — LARGE_INTESTINE

Explore this box plot interactively →