FAM120B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM120B protein abundance is significantly associated with the RNA expression of many other genes, with 5,647 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM120B-associated genes across cancer lineages are PRKN, PACRG, and RSPH3. Each is linked with FAM120B in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM120B-to-partner and partner-to-FAM120B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM120B versus PRKN in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120B→partner) and Y-score (partner→FAM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPRKN →+0.459+0.219.002.00234
UCECPACRG →+0.967+0.171.002<.00133
OVRSPH3 →+0.904+0.398<.001<.00133
OVESRP1 →-0.668-0.320<.001<.00132
OVTBP →+0.495+0.277<.001<.00132
GBMTGFBI →-1.431-0.284<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,647 associations by consensus.

FAM120B vs PRKN — HNSC

Per-sample scatter of FAM120B vs PRKN in HNSC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration