FAM120B

Across TCGA cell cohorts, FAM120B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,892 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FAM120B-associated GO terms across cancer lineages are Termination of RNA polymerase II transcription, Golgi vesicle transport, and Establishment of protein localization to organelle. Each is linked with FAM120B in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM120B-to-partner and partner-to-FAM120B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase II transcription grouped by FAM120B-low versus FAM120B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120B→partner) and Y-score (partner→FAM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.183	+1.246	<.001	<.001	3	16
LARGE_INTESTINE	Golgi vesicle transport →	+0.054	+0.881	<.001	<.001	3	15
PANCREAS	Establishment of protein localization to organelle →	+0.036	+0.558	<.001	<.001	3	15
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.107	+0.682	<.001	.001	3	15
LARGE_INTESTINE	Nuclear export →	+0.076	+0.755	<.001	<.001	3	15
STOMACH	Cytosolic transport →	+0.060	+0.830	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,892 associations by consensus.

Termination of RNA polymerase II transcription by FAM120B expression — LUNG_SCLC

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