FAM120B

Across TCGA cell cohorts, FAM120B mutation is significantly associated with the RNA expression of many other genes, with 112 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM120B-associated genes across cancer lineages are OR5M10, H1-8, and KRTAP3-1. Each is linked with FAM120B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM120B-to-partner and partner-to-FAM120B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5M10 grouped by FAM120B-low versus FAM120B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120B→partner) and Y-score (partner→FAM120B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR5M10 →	+0.019	+5.662	<.001	.002	3	1
BLOOD_Leukemia	H1-8 →	+0.018	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP3-1 →	+0.038	+5.539	<.001	.003	3	1
LARGE_INTESTINE	GCAT →	+1.184	+3.321	.002	.003	3	1
LARGE_INTESTINE	CENPM →	+0.738	+3.169	.002	.009	3	1
LARGE_INTESTINE	HSCB →	+0.579	+3.502	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

OR5M10 by FAM120B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →