FAM117B

Across TCGA patient cohorts, FAM117B RNA expression is significantly associated with the protein abundance of many other proteins, with 20,732 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM117B-associated proteins across cancer lineages are SIN3A, ADNP, and SF3B3. Each is linked with FAM117B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM117B-to-partner and partner-to-FAM117B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM117B versus SIN3A in LUAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM117B→partner) and Y-score (partner→FAM117B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SIN3A →	+0.223	+0.613	<.001	<.001	3	7
LSCC	ADNP →	+0.299	+0.811	<.001	<.001	3	7
LSCC	SF3B3 →	+0.198	+0.940	<.001	<.001	3	7
LSCC	HNRNPU →	+0.213	+1.059	<.001	<.001	3	7
GBM	WDR5 →	+0.262	+0.659	<.001	<.001	3	6
GBM	XRCC6 →	+0.257	+0.562	.004	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,732 associations by consensus.

FAM117B vs SIN3A — LUAD

Explore this scatter interactively →