FAM117A

Across TCGA cell cohorts, FAM117A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,967 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM117A-associated GO terms across cancer lineages are Cholesterol biosynthetic process via lathosterol, RNA catabolic process, and DNA replication-dependent chromatin disassembly. Each is linked with FAM117A in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM117A-to-partner and partner-to-FAM117A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cholesterol biosynthetic process via lathosterol grouped by FAM117A-low versus FAM117A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM117A→partner) and Y-score (partner→FAM117A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cholesterol biosynthetic process via lathosterol →	+0.195	+1.325	<.001	<.001	3	14
BONE	RNA catabolic process →	+0.073	+0.975	<.001	<.001	3	13
BONE	DNA replication-dependent chromatin disassembly →	+0.170	+0.920	<.001	<.001	3	12
BONE	Nucleic acid catabolic process →	+0.051	+0.890	<.001	<.001	3	12
BREAST	Negative regulation of transcription elongation by RNA polymerase II →	+0.098	+0.975	<.001	.007	3	12
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.053	+0.845	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,967 associations by consensus.

Cholesterol biosynthetic process via lathosterol by FAM117A expression — OVARY

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