FAM114A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM114A1 mutation is significantly associated with the RNA expression of many other genes, with 2,617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM114A1-associated genes across cancer lineages are TMEM225, RN7SL578P, and RNU6-23P. Each is linked with FAM114A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM114A1-to-partner and partner-to-FAM114A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM114A1→partner) and Y-score (partner→FAM114A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READTMEM225 →+0.114+5.039<.001.00832
READRN7SL578P →+0.172+5.039<.001.00832
LUADRNU6-23P →+0.405+6.197<.001.00132
LUADRNA5SP66 →+0.315+5.984<.001.00232
LUADOR7K1P →+0.044+6.197<.001.00132
LUADBCAR1P2 →+0.056+5.217.003.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

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