Across TCGA patient cohorts, FAM111B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,212 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM111B-associated proteins across cancer lineages are FEN1, RPL12_S38, and SMC2. Each is linked with FAM111B in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM111B-to-partner and partner-to-FAM111B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111B→partner) and Y-score (partner→FAM111B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FEN1 →	+0.553	+1.178	<.001	<.001	3	10
OV	RPL12_S38 →	+1.103	+1.220	<.001	<.001	3	10
GBM	SMC2 →	+0.695	+1.062	<.001	<.001	3	10
LSCC	SMC4 →	+0.671	+1.380	<.001	<.001	3	10
GBM	MCM2 →	+0.801	+1.125	<.001	<.001	3	10
LUAD	MCM2_S139 →	+0.840	+1.008	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,212 associations by consensus.

Exploration

FAM111B survival (RNA) · tumor vs normal (RNA) · all FAM111B data types