FAM111A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM111A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,446 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM111A-associated proteins across cancer lineages are UBE2L6, PSMB6, and DCK. Each is linked with FAM111A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM111A-to-partner and partner-to-FAM111A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM111A versus UBE2L6 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111A→partner) and Y-score (partner→FAM111A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCUBE2L6 →+0.487+0.448<.001.00135
CCRCCPSMB6 →-0.380-0.307<.001<.00126
HNSCDCK →+0.296+0.510<.001<.00134
GBMDHX15 →+0.219+0.552<.001<.00134
COADGBP1 →+0.619+0.490.003.00434
UCECYWHAZ →-0.318-0.583<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,446 associations by consensus.

FAM111A vs UBE2L6 — LSCC

Per-sample scatter of FAM111A vs UBE2L6 in LSCC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration