FAM111A

Across TCGA patient cohorts, FAM111A protein abundance is significantly associated with the RNA expression of many other genes, with 5,179 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM111A-associated genes across cancer lineages are FAM111B, SKA1, and FAM111A-DT. Each is linked with FAM111A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM111A-to-partner and partner-to-FAM111A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM111A versus FAM111B in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111A→partner) and Y-score (partner→FAM111A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM111B →	+0.971	+0.341	.001	.001	3	6
BRCA	SKA1 →	+0.938	+0.328	.001	<.001	3	5
LSCC	FAM111A-DT →	+0.450	+0.245	<.001	<.001	3	5
LUAD	GINS1 →	+0.842	+0.263	.001	<.001	3	4
BRCA	E2F1 →	+0.869	+0.322	<.001	<.001	3	4
LUAD	SUV39H1 →	+0.559	+0.286	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,179 associations by consensus.

FAM111A vs FAM111B — UCEC

Explore this scatter interactively →