FAM111A

Across TCGA patient cohorts, FAM111A mutation is significantly associated with the RNA expression of many other genes, with 2,365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM111A-associated genes across cancer lineages are RNU6-782P, PIGW, and SPDYE10P. Each is linked with FAM111A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM111A-to-partner and partner-to-FAM111A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-782P grouped by FAM111A-low versus FAM111A-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111A→partner) and Y-score (partner→FAM111A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU6-782P →	+0.660	+4.167	.004	.004	3	3
UCEC	PIGW →	+0.585	+2.584	<.001	<.001	3	2
CESC	SPDYE10P →	+0.029	+4.320	<.001	.007	3	2
UCEC	BTBD10 →	+0.383	+1.942	.003	.002	3	2
UCEC	CENPU →	+0.569	+2.850	.002	.001	3	2
UCEC	SAR1B →	+0.420	+2.510	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,365 associations by consensus.

RNU6-782P by FAM111A expression — STAD

Explore this box plot interactively →