FAM106DP

Across TCGA pan-cancer cohorts, FAM106DP RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated FAM106DP data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher FAM106DP RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM106DP expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

LUSC, THCA, and KIRP are the cancer types where FAM106DP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	IV	0.001	0.673	.014	54	view →
THCA	DFS	Tertile	II,III,IV	0.121	0.691	<.001	36	view →
KIRP	OS	Tertile	IV	0.111	0.503	<.001	36	view →
KIRC	DFS	Tertile	IV	0.273	0.655	.004	33	view →
PCPG	OS	Tertile	All	0.679	0.981	<.001	27	view →
PAAD	OS	Tertile	All	0.712	0.335	.010	18	view →
COAD	OS	Tertile	III,IV	0.503	0.793	.014	18	view →
LGG	OS	Tertile	All	0.802	0.924	.009	15	view →
BRCA	OS	Tertile	II,III,IV	0.488	0.579	.022	12	view →
READ	DFS	Tertile	III,IV	0.328	0.585	.048	9	view →
LIHC	DFS	Tertile	All	0.063	0.555	<.001	9	view →
PRAD	DFS	Tertile	All	0.785	0.894	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

FAM106DP–LUSC (OS)

Open the LUSC breakdown →