FAM106DP

Across TCGA pan-cancer cohorts, FAM106DP RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FAM106DP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FAM106DP RNA is repressed in tumor relative to normal tissue. In most cancer types FAM106DP is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and LUSC are the cancer types where FAM106DP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM106DP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.135	<.001	9	view →
THCA	All	All	−0.034	<.001	4	view →
LUSC	Female	All	−0.103	.011	2	view →
KIRC	All	All	−0.019	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

FAM106DP–COAD

Open the COAD breakdown →