FAM106A

Across TCGA patient cohorts, FAM106A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,646 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FAM106A-associated GO terms across cancer lineages are Protein localization to vacuole, Protein targeting to vacuole, and Establishment of protein localization to vacuole. Each is linked with FAM106A in more than 28 cancer types. Because this analysis shows association rather than direction, both FAM106A-to-partner and partner-to-FAM106A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by FAM106A-low versus FAM106A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM106A→partner) and Y-score (partner→FAM106A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to vacuole →	+0.048	+0.196	<.001	<.001	3	29
THYM	Protein targeting to vacuole →	+0.052	+0.606	<.001	<.001	3	29
THYM	Establishment of protein localization to vacuole →	+0.054	+0.578	<.001	<.001	3	28
UCS	Telomere maintenance →	+0.047	+0.565	<.001	.001	3	28
UCS	Cytosolic transport →	+0.045	+0.611	<.001	<.001	3	28
THYM	Protein sumoylation →	+0.045	+0.615	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,646 associations by consensus.

Protein localization to vacuole by FAM106A expression — STAD

Explore this box plot interactively →