FAM104B

Across TCGA patient cohorts, FAM104B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM104B-associated proteins across cancer lineages are HUWE1, CTPS2, and GPKOW. Each is linked with FAM104B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM104B-to-partner and partner-to-FAM104B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM104B versus HUWE1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM104B→partner) and Y-score (partner→FAM104B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HUWE1 →	+0.230	+0.355	<.001	<.001	3	6
HNSC	CTPS2 →	+0.325	+0.357	<.001	<.001	3	5
LSCC	GPKOW →	+0.228	+0.455	<.001	<.001	3	5
GBM	RBM10 →	+0.244	+0.307	<.001	<.001	3	5
LSCC	MTA1 →	+0.319	+0.376	<.001	.003	3	5
OV	NONO →	+0.209	+0.642	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,839 associations by consensus.

FAM104B vs HUWE1 — GBM

Explore this scatter interactively →