FAM104B

Across TCGA cell cohorts, FAM104B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,531 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM104B-associated GO terms across cancer lineages are Proton-transporting two-sector ATPase complex assembly, Mitochondrial proton-transporting ATP synthase complex assembly, and Proton-transporting ATP synthase complex assembly. Each is linked with FAM104B in more than 11 cancer types. Because this analysis shows association rather than direction, both FAM104B-to-partner and partner-to-FAM104B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton-transporting two-sector ATPase complex assembly grouped by FAM104B-low versus FAM104B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM104B→partner) and Y-score (partner→FAM104B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Proton-transporting two-sector ATPase complex assembly →	+0.110	+0.860	.001	<.001	3	12
BREAST	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.096	+0.847	.002	.002	3	12
BREAST	Proton-transporting ATP synthase complex assembly →	+0.096	+0.847	.002	.002	3	12
STOMACH	Positive regulation of fibroblast growth factor receptor signaling pathway →	-0.192	-0.704	.001	.007	3	10
BREAST	Base-excision repair →	+0.080	+1.006	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cell-substrate junction assembly →	-0.135	-0.787	.004	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

Proton-transporting two-sector ATPase complex assembly by FAM104B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →