FAM102A

Across TCGA pan-cancer cohorts, FAM102A Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FAM102A data layer compared with 22 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM102A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM102A expression acts as an unfavorable survival marker.

SKCM, DLBC, and STAD are the cancer types where FAM102A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.252	0.786	<.001	42	view →
DLBC	OS	Median	All	0.053	0.936	<.001	12	view →
STAD	DFS	Median	All	0.207	0.592	.010	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FAM102A–SKCM (OS)

Open the SKCM breakdown →