FAHD2B

Across TCGA patient cohorts, FAHD2B mutation is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAHD2B-associated genes across cancer lineages are RNU6-836P, TUBB1P2, and RNU6-572P. Each is linked with FAHD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAHD2B-to-partner and partner-to-FAHD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-836P grouped by FAHD2B-low versus FAHD2B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAHD2B→partner) and Y-score (partner→FAHD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-836P →	+1.008	+5.712	<.001	.003	3	2
COAD	TUBB1P2 →	+0.039	+7.741	<.001	.009	3	2
COAD	RNU6-572P →	+0.442	+7.741	<.001	.009	3	2
UCEC	RNY1P1 →	+0.250	+4.113	<.001	.001	3	2
UCEC	ATF4P1 →	+0.061	+3.132	<.001	.003	3	2
UCEC	RNA5SP421 →	+0.772	+2.603	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

RNU6-836P by FAHD2B expression — LUAD

Explore this box plot interactively →