Across TCGA pan-cancer cohorts, FAF1-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FAF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FAF1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types FAF1-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, KIRC, and BRCA are the cancer types where FAF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.222	.003	3	view →
KIRC	All	All	+0.087	<.001	3	view →
BRCA	All	III,IV	−0.152	.028	2	view →
LUSC	Male	III,IV	−0.300	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: FAF1-AS1 RNA expression & survival · all FAF1-AS1 data types