Across TCGA patient cohorts, FADS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,596 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FADS3-associated proteins across cancer lineages are FLNA, ICAM1, and TMEM238. Each is linked with FADS3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FADS3-to-partner and partner-to-FADS3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS3→partner) and Y-score (partner→FADS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FLNA →	+0.434	+0.489	.006	<.001	3	5
BRCA	ICAM1 →	+0.792	+1.092	<.001	<.001	3	5
HNSC	TMEM238 →	-0.697	-0.974	<.001	<.001	3	4
COAD	C1QA →	+0.607	+0.517	<.001	.002	3	4
LSCC	C1R →	+0.563	+0.692	<.001	<.001	3	4
BRCA	DBN1 →	+0.464	+0.755	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,596 associations by consensus.

Exploration

FADS3 survival (RNA) · tumor vs normal (RNA) · all FADS3 data types