Across TCGA patient cohorts, FADS3 mutation is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FADS3-associated genes across cancer lineages are KRT19P6, MIR6750, and RN7SL402P. Each is linked with FADS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FADS3-to-partner and partner-to-FADS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS3→partner) and Y-score (partner→FADS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	KRT19P6 →	+0.076	+3.096	<.001	.007	3	2
SKCM	MIR6750 →	+0.418	+2.353	<.001	.002	3	2
LUSC	RN7SL402P →	+0.240	+4.261	.003	.008	3	2
BLCA	MIR4773-1 →	+0.723	+7.307	<.001	<.001	3	1
SKCM	MIR6829 →	+0.220	+2.642	.001	.003	3	1
LUAD	RNA5SP85 →	+0.318	+4.730	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

Exploration

FADS3 survival (RNA) · tumor vs normal (RNA) · all FADS3 data types