FADS2B

Across TCGA pan-cancer cohorts, FADS2B RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated FADS2B data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher FADS2B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FADS2B expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

BRCA, LUSC, and KIRC are the cancer types where FADS2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.836	0.908	.006	75	view →
LUSC	OS	Tertile	II,III,IV	0.494	0.669	.003	75	view →
KIRC	OS	Tertile	All	0.462	0.655	.001	72	view →
KIRP	OS	Tertile	II,III,IV	0.203	0.761	<.001	54	view →
CESC	DFS	Tertile	IV	0.224	0.600	.005	48	view →
THYM	DFS	Tertile	All	0.584	0.920	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
UCS	OS	Tertile	III,IV	0.812	0.284	.031	24	view →
READ	DFS	Median	IV	0.179	0.936	.010	15	view →
THCA	OS	Tertile	IV	0.520	0.838	.046	12	view →
ESCA	DFS	Quartile	III,IV	0.710	0.347	.009	12	view →
LUAD	DFS	Median	All	0.870	0.782	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

FADS2B–BRCA (DFS)

Open the BRCA breakdown →