FADS1

Across TCGA patient cohorts, FADS1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,433 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FADS1-associated genes across cancer lineages are FADS2, NUF2, and CENPI. Each is linked with FADS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FADS1-to-partner and partner-to-FADS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FADS1 versus FADS2 in OV, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FADS1→partner) and Y-score (partner→FADS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FADS2 →	+1.920	+1.392	<.001	<.001	3	6
UCEC	NUF2 →	+0.997	+0.473	.001	.005	3	6
UCEC	CENPI →	+0.926	+0.640	<.001	<.001	3	5
OV	LMNB1 →	+1.059	+0.860	.004	.005	2	6
LUAD	KIF14 →	+0.868	+0.428	<.001	<.001	3	5
UCEC	CHEK1 →	+0.790	+0.614	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,433 associations by consensus.

FADS1 vs FADS2 — OV

Explore this scatter interactively →