FABP7

Across TCGA patient cohorts, FABP7 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP7-associated genes across cancer lineages are 14-3-3_beta, ERK2, and Heregulin. Each is linked with FABP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP7-to-partner and partner-to-FABP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by FABP7-low versus FABP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP7→partner) and Y-score (partner→FABP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.126	-3.432	.003	.005	3	1
UCEC	ERK2 →	+0.176	+1.700	.031	.044	3	1
UCEC	Heregulin →	-0.128	-3.156	.014	.018	3	1
UCEC	JNK2 →	+0.279	+2.594	<.001	.006	3	1
UCEC	MEK1 →	+0.383	+2.321	.013	.034	3	1
UCEC	p62 Lck ligand →	+0.319	+2.222	.021	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

14-3-3_beta by FABP7 expression — UCEC

Explore this box plot interactively →