FABP7

Across TCGA pan-cancer cohorts, FABP7 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FABP7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FABP7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FABP7 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

KIRC, THCA, and BRCA are the cancer types where FABP7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FABP7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	+7.695	<.001	12	view →
THCA	Male	All	−0.101	<.001	7	view →
BRCA	All	III,IV	−2.721	<.001	6	view →
HNSC	All	All	−1.163	<.001	6	view →
KICH	Female	All	−0.045	.007	3	view →
LUSC	Male	All	+0.614	.002	2	view →
PRAD	All	All	−0.488	<.001	2	view →
LIHC	All	All	+0.024	.011	2	view →
LUAD	All	All	+0.474	.023	1	view →
COAD	All	III,IV	−0.042	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FABP7–KIRC

Open the KIRC breakdown →