FABP6

Across TCGA pan-cancer cohorts, FABP6 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FABP6 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FABP6 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated FABP6 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

BLCA, PRAD, and UCEC are the cancer types where FABP6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	III,IV	0.506	0.366	<.001	26	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	OS	Median	All	0.598	0.872	.031	3	view →
SKCM	OS	Median	II,III,IV	0.325	0.744	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FABP6–BLCA (OS)

Open the BLCA breakdown →