FABP6

Across TCGA pan-cancer cohorts, FABP6 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of FABP6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FABP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FABP6 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

KIRC, COAD, and HNSC are the cancer types where FABP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FABP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+5.052	<.001	12	view →
COAD	Female	III,IV	+4.142	<.001	11	view →
HNSC	All	III,IV	+1.460	<.001	11	view →
READ	All	II,III,IV	+4.517	<.001	7	view →
KIRP	Male	III,IV	+3.014	<.001	7	view →
BLCA	All	All	+2.068	.001	6	view →
BRCA	All	II,III,IV	+0.763	<.001	6	view →
LIHC	All	All	+0.338	<.001	6	view →
THCA	All	All	+0.210	.010	6	view →
KICH	All	II,III,IV	+1.702	.002	5	view →
STAD	All	All	+1.151	.004	4	view →
CHOL	All	All	+1.067	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

FABP6–KIRC

Open the KIRC breakdown →