FABP6

Across TCGA pan-cancer cohorts, FABP6 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FABP6 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FABP6 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FABP6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where FABP6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.804	0.238	<.001	14	view →
CCRCC	DFS	Median	III,IV	0.395	0.733	.004	11	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.818	.005	10	view →
PDAC	DFS	Tertile	All	0.578	0.292	.025	9	view →
UCEC	DFS	Quartile	All	0.870	1.000	.035	4	view →
GBM	DFS	Tertile	All	0.778	0.663	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FABP6–LUAD (DFS)

Open the LUAD breakdown →