FABP6

Across TCGA patient cohorts, FABP6 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP6-associated genes across cancer lineages are A-Raf_pS299, Ku80, and VEGFR2. Each is linked with FABP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP6-to-partner and partner-to-FABP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by FABP6-low versus FABP6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP6→partner) and Y-score (partner→FABP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.174	-3.169	.003	.019	3	1
UCEC	Ku80 →	+0.287	+2.817	.015	.036	3	1
UCEC	VEGFR2 →	+0.293	+3.009	.049	.019	3	1
UCEC	Di-Ras3 →	-0.149	-2.321	.046	.035	3	1
UCEC	AMPK_pT172 →	+0.432	+2.335	.036	.020	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

A-Raf_pS299 by FABP6 expression — UCEC

Explore this box plot interactively →