FABP3

Across TCGA pan-cancer cohorts, FABP3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FABP3 data layer compared with 5 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher FABP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FABP3 expression acts as an unfavorable survival marker, although some lineages such as KIRC and ACC show a favorable association.

UVM, KIRC, and ACC are the cancer types where FABP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.434	0.856	<.001	119	view →
KIRC	OS	Median	All	0.691	0.568	<.001	110	view →
ACC	DFS	Median	All	0.733	0.435	.001	83	view →
KIRP	DFS	Quartile	All	1.000	0.479	.002	69	view →
COAD	DFS	Tertile	All	0.424	0.663	<.001	46	view →
LUAD	DFS	Median	All	0.838	0.741	<.001	39	view →
LIHC	OS	Tertile	All	0.441	0.678	.003	32	view →
STAD	OS	Quartile	All	0.454	0.762	.011	22	view →
MESO	OS	Median	IV	0.338	0.770	.003	22	view →
ESCA	OS	Tertile	All	0.448	0.680	.004	14	view →
DLBC	DFS	Median	II,III,IV	0.890	0.542	.016	13	view →
CESC	OS	Median	IV	0.596	0.111	.028	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FABP3–UVM (OS)

Open the UVM breakdown →