FABP3

Across TCGA pan-cancer cohorts, FABP3 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FABP3’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where FABP3 RNA is repressed in tumor relative to normal tissue. In most cancer types FABP3 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

UCEC, LUSC, and KIRP are the cancer types where FABP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FABP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	−2.457	<.001	6	view →
LUSC	Male	II,III,IV	−1.814	<.001	6	view →
KIRP	Male	II,III,IV	−2.059	.006	5	view →
KIRC	Male	All	−0.878	<.001	5	view →
HNSC	Male	All	−1.540	.010	3	view →
PRAD	All	All	−1.134	<.001	2	view →
PAAD	Female	All	−0.964	.038	2	view →
COAD	Male	All	−0.789	.009	2	view →
LUAD	All	All	−0.535	.038	2	view →
READ	All	II,III,IV	−1.077	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FABP3–UCEC

Open the UCEC breakdown →