FABP1

Across TCGA patient cohorts, FABP1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP1-associated genes across cancer lineages are INPP4B, PAI-1, and FASN. Each is linked with FABP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP1-to-partner and partner-to-FABP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by FABP1-low versus FABP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP1→partner) and Y-score (partner→FABP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.348	-2.999	.011	.035	3	2
SKCM	PAI-1 →	+0.844	+3.017	.026	.019	3	2
UCEC	FASN →	+0.352	+2.222	.035	.011	3	1
UCEC	JNK_pT183_Y185 →	-0.181	-3.321	.011	.010	3	1
UCEC	Ku80 →	+0.232	+1.713	.020	.027	3	1
UCEC	Notch1 →	+0.269	+3.594	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

INPP4B by FABP1 expression — UCEC

Explore this box plot interactively →