fatty acid binding protein 1Genealiases: FABPL · L-FABP
Q-omics provides the consensus-scored FABP1 profile across patient tissues and cancer cell-line models. FABP1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, FABP1 is differentially expressed in 11, with the highest sampling consensus in KIRP. Additionally, FABP1 RNA expression shows 11,483 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, KIRP, and TGCT as cancer lineages where FABP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FABP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FABP1 survival associations across molecular data types. FABP1 RNA expression shows survival associations in the most cancer types (22), followed by mutation status (6) and mass-spec protein abundance (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FABP1 RNA expression–survival associations across cancer types. High FABP1 expression shows unfavorable associations in HNSC, ACC, UCEC and CHOL, but favorable associations in KIRC and LIHC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for FABP1 RNA expression.
This table summarizes FABP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11, while mass-spec protein shows differences in 4. The strongest signals are observed in KIRP for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for FABP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FABP1 shows lower tumor expression in KIRP, COAD, KIRC, KICH, BRCA and CHOL. The KIRP box plot shows higher FABP1 RNA expression in normal versus tumor tissue (log2 FC = −5.274, t-test p < 0.001).
This table shows molecular features associated with FABP1 in patient tissues and cancer cell lines. In patient samples, FABP1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, FABP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and LARGE_INTESTINE.
