FAAH

Across TCGA pan-cancer cohorts, FAAH mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FAAH data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FAAH mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FAAH expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where FAAH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.928	0.749	.004	24	view →
LSCC	DFS	Median	II,III,IV	0.836	1.000	.005	17	view →
LUAD	DFS	Median	All	0.875	0.958	.005	6	view →
GBM	DFS	Quartile	All	0.873	0.601	.010	5	view →
HNSC	DFS	Tertile	III,IV	0.915	0.724	.028	3	view →
PDAC	OS	Median	III,IV	0.363	0.719	.032	2	view →
UCEC	OS	Tertile	All	1.000	0.904	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FAAH–CCRCC (OS)

Open the CCRCC breakdown →