FAAH

Across TCGA pan-cancer cohorts, FAAH RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of FAAH’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where FAAH RNA is repressed in tumor relative to normal tissue. In most cancer types FAAH is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and KIRP are the cancer types where FAAH tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAAH RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−2.028	<.001	11	view →
THCA	Male	IV	−1.709	<.001	11	view →
KIRP	All	III,IV	−1.040	<.001	7	view →
BRCA	All	III,IV	+0.841	<.001	6	view →
LUSC	All	II,III,IV	−1.233	<.001	4	view →
STAD	Male	All	+1.036	<.001	4	view →
COAD	All	All	+0.428	.009	3	view →
CHOL	Female	All	+1.366	.028	2	view →
UCEC	All	All	+1.261	<.001	2	view →
PRAD	All	All	+0.650	.001	2	view →
HNSC	Female	IV	−1.311	.042	1	view →
BLCA	All	III,IV	+1.072	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

FAAH–KICH

Open the KICH breakdown →