FAAH

Across TCGA patient cohorts, FAAH mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAAH-associated genes across cancer lineages are Chk2_pT68, TSC1, and ERK2. Each is linked with FAAH in more than 1 cancer types. Because this analysis shows association rather than direction, both FAAH-to-partner and partner-to-FAAH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chk2_pT68 grouped by FAAH-low versus FAAH-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAAH→partner) and Y-score (partner→FAAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Chk2_pT68 →	-0.185	-2.115	.023	.019	3	2
UCEC	TSC1 →	-0.183	-3.130	.014	.018	3	1
UCEC	ERK2 →	+0.214	+2.115	.010	.019	2	1
UCEC	4E-BP1 →	+0.273	+2.837	.021	.035	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Chk2_pT68 by FAAH expression — UCEC

Explore this box plot interactively →