FA2H

Across TCGA pan-cancer cohorts, FA2H Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FA2H data layer compared with 19 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FA2H Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FA2H expression acts as an unfavorable survival marker.

BLCA, LUSC, and STAD are the cancer types where FA2H Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.130	0.720	<.001	48	view →
LUSC	OS	Median	All	0.168	0.675	.023	18	view →
STAD	OS	Median	II,III,IV	0.003	0.660	<.001	12	view →
SCLC	OS	Median	All	0.055	0.708	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	II,III,IV	0.353	0.735	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FA2H–BLCA (OS)

Open the BLCA breakdown →