F9

Across TCGA pan-cancer cohorts, F9 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated F9 data layer compared with 11 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher F9 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated F9 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

COAD, LUAD, and CCRCC are the cancer types where F9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.019	24	view →
LUAD	DFS	Tertile	II,III,IV	0.737	0.964	.003	13	view →
CCRCC	DFS	Quartile	All	1.000	0.731	.002	9	view →
LSCC	DFS	Median	II,III,IV	0.824	1.000	.002	5	view →
UCEC	DFS	Median	III,IV	0.445	0.904	.037	4	view →
PDAC	DFS	Tertile	IV	0.741	0.205	.024	3	view →
GBM	OS	Tertile	All	0.274	0.516	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

F9–COAD (DFS)

Open the COAD breakdown →