F8A1

Across TCGA cell cohorts, F8A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,431 significant associations in total. CNS shows the largest number of these associations.

The most reproducible F8A1-associated GO terms across cancer lineages are Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, Latent virus replication, and Release from viral latency. Each is linked with F8A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both F8A1-to-partner and partner-to-F8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway grouped by F8A1-low versus F8A1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F8A1→partner) and Y-score (partner→F8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.096	+0.823	.002	.002	2	9
URINARY_TRACT	Latent virus replication →	+0.100	+1.297	<.001	.001	2	9
URINARY_TRACT	Release from viral latency →	+0.100	+1.297	<.001	.001	2	9
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.069	+1.112	.001	<.001	3	7
BONE	Positive regulation of microtubule nucleation →	+0.127	+1.342	.003	.002	3	7
URINARY_TRACT	Negative regulation of protein modification by small protein conjugation or removal →	+0.062	+1.283	.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,431 associations by consensus.

Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway by F8A1 expression — LARGE_INTESTINE

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