F8A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, F8A1 protein abundance is significantly associated with the go_rna of many other GO terms, with 858 significant associations in total. BONE shows the largest number of these associations.

The most reproducible F8A1-associated GO terms across cancer lineages are Lymphocyte migration into lymphoid organs, Negative regulation of reactive oxygen species biosynthetic process, and Interleukin-5-mediated signaling pathway. Each is linked with F8A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both F8A1-to-partner and partner-to-F8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lymphocyte migration into lymphoid organs grouped by F8A1-low versus F8A1-high in STOMACH.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F8A1→partner) and Y-score (partner→F8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHLymphocyte migration into lymphoid organs →+0.251+1.025.001.00136
SOFT_TISSUENegative regulation of reactive oxygen species biosynthetic process →+0.222+1.020.003<.00134
OESOPHAGUSInterleukin-5-mediated signaling pathway →-0.151-1.380<.001.00834
CNSRegulation of hydrogen peroxide biosynthetic process →+0.200+1.166.003.00334
BLOOD_LymphomaPositive regulation of receptor recycling →+0.136+1.097.004.00433
BLOOD_LymphomaRegulation of T cell mediated immunity →+0.074+0.902.004<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

Lymphocyte migration into lymphoid organs by F8A1 expression — STOMACH

Box plot of Lymphocyte migration into lymphoid organs in F8A1-low vs F8A1-high samples in STOMACH.

Explore this box plot interactively →

Exploration