F8A1

Across TCGA cell cohorts, F8A1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible F8A1-associated genes across cancer lineages are TSHB, WNT9B, and OR10Z1. Each is linked with F8A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both F8A1-to-partner and partner-to-F8A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by F8A1-low versus F8A1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F8A1→partner) and Y-score (partner→F8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TSHB →	+0.047	+5.000	<.001	.006	3	1
PANCREAS	WNT9B →	+0.013	+5.614	<.001	.002	3	1
PANCREAS	OR10Z1 →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	LEUTX →	+1.449	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TSHB by F8A1 expression — PANCREAS

Explore this box plot interactively →