F2RL3

Across TCGA patient cohorts, F2RL3 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible F2RL3-associated genes across cancer lineages are RN7SL554P, RNA5SP414, and RNU6-206P. Each is linked with F2RL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both F2RL3-to-partner and partner-to-F2RL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL554P grouped by F2RL3-low versus F2RL3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F2RL3→partner) and Y-score (partner→F2RL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL554P →	+0.115	+4.685	.005	.007	3	2
UCEC	RNA5SP414 →	+1.035	+3.255	<.001	.003	3	2
UCEC	RNU6-206P →	+0.275	+4.660	<.001	.003	3	2
UCEC	RNA5SP416 →	+0.968	+3.224	<.001	.004	3	2
SKCM	OR4C4P →	+0.014	+5.058	<.001	.001	3	2
SKCM	RNA5-8SP4 →	+0.076	+4.049	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

RN7SL554P by F2RL3 expression — BLCA

Explore this box plot interactively →