F2RL1

Across TCGA patient cohorts, F2RL1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,193 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible F2RL1-associated genes across cancer lineages are CDKN2AIPNL, LINC00398, and TMPRSS11F. Each is linked with F2RL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both F2RL1-to-partner and partner-to-F2RL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, F2RL1 versus CDKN2AIPNL in LSCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F2RL1→partner) and Y-score (partner→F2RL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDKN2AIPNL →	+0.526	+0.796	<.001	<.001	3	2
UCEC	LINC00398 →	-0.530	-1.113	.004	.001	3	2
GBM	TMPRSS11F →	+0.521	+1.110	.004	.004	3	2
CCRCC	PPP1R26-AS1 →	+0.862	+0.684	<.001	.002	3	2
GBM	ADAP1 →	+0.864	+0.710	.003	.005	3	2
GBM	ATE1 →	+0.498	+0.773	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,193 associations by consensus.

F2RL1 vs CDKN2AIPNL — LSCC

Explore this scatter interactively →