F2RL1

Across TCGA cell cohorts, F2RL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible F2RL1-associated GO terms across cancer lineages are Mature conventional dendritic cell differentiation, Regulation of renin secretion into blood stream, and Negative regulation of toll-like receptor 3 signaling pathway. Each is linked with F2RL1 in more than 16 cancer types. Because this analysis shows association rather than direction, both F2RL1-to-partner and partner-to-F2RL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mature conventional dendritic cell differentiation grouped by F2RL1-low versus F2RL1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F2RL1→partner) and Y-score (partner→F2RL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Mature conventional dendritic cell differentiation →	+1.822	+3.918	<.001	<.001	3	17
BREAST	Regulation of renin secretion into blood stream →	+1.084	+1.780	<.001	<.001	3	15
URINARY_TRACT	Negative regulation of toll-like receptor 3 signaling pathway →	+0.265	+2.844	<.001	<.001	3	12
BONE	Positive regulation of glomerular filtration →	+1.213	+1.886	.001	.002	2	12
SKIN	Positive regulation of phagocytosis, engulfment →	+0.149	+1.912	.007	<.001	3	11
SKIN	Positive regulation of membrane invagination →	+0.149	+1.912	.007	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Mature conventional dendritic cell differentiation by F2RL1 expression — CNS

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