F2R

Across TCGA cell cohorts, F2R RNA expression is significantly associated with the go_rna of many other GO terms, with 4,800 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible F2R-associated GO terms across cancer lineages are Positive regulation of collagen metabolic process, Regulation of renin secretion into blood stream, and Positive regulation of collagen biosynthetic process. Each is linked with F2R in more than 13 cancer types. Because this analysis shows association rather than direction, both F2R-to-partner and partner-to-F2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of collagen metabolic process grouped by F2R-low versus F2R-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F2R→partner) and Y-score (partner→F2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of collagen metabolic process →	+0.243	+2.544	<.001	.003	3	14
BLOOD_Myeloma	Regulation of renin secretion into blood stream →	+1.897	+3.472	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of collagen biosynthetic process →	+0.233	+2.275	<.001	.001	3	14
PANCREAS	Regulation of collagen metabolic process →	+0.142	+1.510	<.001	.001	3	12
BONE	Wound healing involved in inflammatory response →	+0.242	+2.632	<.001	<.001	3	12
BREAST	Regulation of cell-substrate junction assembly →	+0.121	+2.333	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,800 associations by consensus.

Positive regulation of collagen metabolic process by F2R expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →