F13B

Across TCGA pan-cancer cohorts, F13B mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated F13B data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher F13B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated F13B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

COAD, LUAD, and CCRCC are the cancer types where F13B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.864	1.000	.018	48	view →
LUAD	OS	Median	III,IV	0.462	0.771	<.001	43	view →
CCRCC	OS	Median	IV	1.000	0.451	.016	15	view →
UCEC	DFS	Median	III,IV	0.424	1.000	.003	12	view →
LSCC	DFS	Median	II,III,IV	0.840	1.000	.007	9	view →
HNSC	DFS	Median	II,III,IV	0.548	0.729	.023	4	view →
PDAC	OS	Median	IV	0.836	0.491	.024	3	view →
GBM	DFS	Quartile	All	0.563	0.240	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

F13B–COAD (DFS)

Open the COAD breakdown →