F13A1

Across TCGA pan-cancer cohorts, F13A1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated F13A1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher F13A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated F13A1 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

CCRCC, COAD, and LUAD are the cancer types where F13A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.627	0.900	.005	42	view →
COAD	DFS	Median	II,III,IV	0.875	1.000	.015	36	view →
LUAD	DFS	Median	III,IV	0.485	0.996	.001	16	view →
GBM	OS	Median	All	0.751	0.965	.001	11	view →
LSCC	OS	Median	All	0.920	1.000	.008	5	view →
OV	DFS	Median	All	1.000	0.864	.035	4	view →
UCEC	DFS	Tertile	II,III,IV	0.415	0.835	.047	4	view →
HNSC	DFS	Tertile	II,III,IV	0.448	0.708	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

F13A1–CCRCC (DFS)

Open the CCRCC breakdown →