F13A1

Across TCGA cell cohorts, F13A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 853 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible F13A1-associated GO terms across cancer lineages are Transcription elongation by RNA polymerase II, Basement membrane disassembly, and Positive regulation of mitochondrial membrane permeability. Each is linked with F13A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both F13A1-to-partner and partner-to-F13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation by RNA polymerase II grouped by F13A1-low versus F13A1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F13A1→partner) and Y-score (partner→F13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Transcription elongation by RNA polymerase II →	+0.087	+0.054	<.001	.003	3	4
SOFT_TISSUE	Basement membrane disassembly →	+1.143	+1.238	<.001	.003	3	4
SOFT_TISSUE	Positive regulation of mitochondrial membrane permeability →	+0.049	+1.317	.007	.003	3	4
BLOOD_Lymphoma	Respiratory gaseous exchange by respiratory system →	-0.090	-0.807	.001	.005	3	4
SOFT_TISSUE	Vitamin A metabolic process →	+1.488	+1.765	<.001	.001	3	3
UPPER_AERODIGESTIVE_TRACT	Monoatomic anion transmembrane transport →	-0.074	-0.054	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

Transcription elongation by RNA polymerase II by F13A1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →